
Structure-activity relationship and chemical biology for bioactive compounds from natural and organic synthesis
Faculty
- NameE-mail Address
- Position
- Degree
- HASHIMOTO Makoto
- Professor
- Ph. D. Pharm.
hasimoto[at]agr.hokudai.ac.jp
Researchers’ directory- SAKIHAMA Yasuko
- Professor
- Doctor (Science)
sakihama[at]agr.hokudai.ac.jp
Researchers’ directory- MURAI Yuta
- Associate Professor
- Ph. D. Agr.
ymurai[at]agr.hokudai.ac.jp
Researchers’ directoryWebsite
Laboratory: https://molecochem.wixsite.com/website-3
Professor Hashimoto: http://lmec2.blog.fc2.com/
Selected Publications
- Makoto Hashimoto*, Tomoya Nakagita, Takumi Misaka, Recent progress in the use of diaziridine-based sweetener derivatives to elucidate the chemoreception mechanism of the sweet taste receptor, RSC Advances, 11, 32236-32247 (2021); https://pubs.rsc.org/en/content/articlelanding/2021/ra/d1ra04831g
- Makoto Hashimoto*, 00111.Diaziridines and diazirines, In Three-membered Heterocycles, and all Fused Systems with a Three-membered Heterocyclic Ring, Comprehensive Heterocyclic Chemistry IV (Reference Module in Chemistry, Molecular Sciences and Chemical Engineering 2019, 1-16 (2019); https://doi.org/10.1016/B978-0-12-409547-2.14763-8
- Yasuko Sakihama, Makiko Maeda, Makoto Hashimoto, Satoshi Tahara and Yasuyuki Hashidoko. Beetroot betalain inhibits peroxynitrite-mediated tyrosine nitration and DNA strand cleavage. Free Radical Research 46, 93-99 (2012)
- Lei Wang, Akiko Ishida, Yasuyuki Hashidoko, Makoto Hashimoto*, Dehydrogenation of NH-NH Bond Triggered by Potassium t-Butoxide in Liquid NH3, Angew. Chem. Int. Ed., 56, 870-873 (2017), German Ed: Angew. Chem., 129, 888 – 891(2017); DOI: 10.1002/anie.201610371
- Zetryana Puteri Tachrim, Lei Wang, Yuta Murai, Takuma Yoshida, Natsumi Kurokawa, Fumina Ohashi, Yasuyuki Hashidoko, Makoto Hashimoto*, Triflouromethanesulfonic Acid as Acylation Catalyst: Special Feature for C- and/or O-Acylation Reactions, Catalysts, 7(2), 40 (2017); doi:10.3390/catal7020040